We work together with athletes, trainers and other health care professionals to customize medications which meet specific needs.Athletes, coaches, trainers, team physicians, physical therapists, and even the "weekend warrior" are faced with problems such as:inflammation muscle spasms fungal infections of the skin and nails (athlete's foot, jock itch, and onychomycosis) hemorrhoids excessive perspiration.
LOYOLA PHARMACY compounding specialists can help these problems and more, with customized medications that contain the most appropriate ingredients in the best vehicle to most efficiently provide the needed drug to the affected area. Please contact our compounding pharmacist for more information or to discuss "problem-solving" therapies.
Transdermal therapy to decrease side effects medications that relieve pain, reduce inflammation, and relax muscles can have side effects that are detrimental to athletic performance, such as drowsiness. However, when these medications are administered transdermally, the therapeutic benefit can be enhanced while significantly reducing the risk of adverse effects. For example, research has shown that topically applied ketoprofen provides a high local concentration of drug below the site of application but decreases systemic exposure and significantly reduces the risk of gastrointestinal upset or bleeding. When properly compounded into an appropriate base, tissue concentrations of ketoprofen were found to be 100-fold greater below the application site (knee) compared to systemic concentrations. Muscle relaxants can be similarly prepared to minimize the risk of drowsiness.
The following article concludes: "Topical non-steroidal anti-inflammatory drugs are effective in relieving pain in acute and chronic conditions. "BMJ. 1998 Jan 31;316(7128):333-8 Quantitative systematic review of topically applied non-steroidal anti-inflammatory drugs.Moore RA, Tramer MR, Carroll D, Wiffen PJ, McQuay HJ.University of Oxford, Oxford Radcliffe Hospital, Headington. The abstract of this article can be viewed online. Go to PubMed:www.ncbi.nlm.nih.gov/PubMedIn the search box, enter the following PMID: 9487165Free full text article available at bmj.com:http://bmj.bmjjournals.com/cgi/content/full/316/7128/333 The following article reports "The systemic concentrations of ketoprofen have also been found to be 100 fold lower compared to tissue concentrations below the application site in patients undergoing knee joint surgery. Topically applied ketoprofen thus provides high local concentration below the site of application but lower systemic exposure. "Pharm Res. 1996 Jan;13(1):168-72Percutaneous absorption of ketoprofen from different anatomical sites in man.Shah AK, Wei G, Lanman RC, Bhargava VO, Weir SJ.Pfizer Inc., Central Research Division, Groton, Connecticut 06340, USA.The abstract of this article can be viewed online. Go to PubMed:www.ncbi.nlm.nih.gov/PubMed In the search box, enter the following PMID: 8668669